SEDATIVE DRUGS FOR INTUBATION – HOW THEY HELP IN CRITICAL CARE

two. Histamine Receptor Antagonism: Some sedatives, like antihistamines, exert their sedative effects by blocking histamine receptors from the Mind, significantly H1 receptors. Histamine performs a task in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness.Don’t mix sedatives alongside one another or with other drug